SMART
VHH NANOBODY
DISCOVERY
TWO PLATFORMS, ONE MISSION
Optimized for ImmunoPET, ImmunoRLT,
CAR-T Immunotherapy and Next Generation ELISA
Smart VHH Nanobody Discovery
Cortalix offers cutting-edge VHH Nanobody (single-domain antibody) services through a unique, dual approach:
- Synthetic libraries: animal‑free, rapid, and highly adaptive. Ideal for fast screening, modular formats, or high-throughput projects.
- Immune libraries: derived from llama immunizations. Providing high natural affinity and deep epitope coverage for complex targets.
Our hybrid platform gives you the flexibility to choose the best discovery route for each project, with seamless downstream integration.
Whether you’re developing a diagnostic, therapeutic, or analytical research tool, we support you all the way, with expert services in CDR grafting, humanization, affinity maturation, conjugation, and more.
What We Offer
Our Service
Description
Discovery via Immune & Synthetic Libraries
Choose the best fit, or both, for your target and strategy
Lead Optimization
CDR grafting, humanization, stability profiling, affinity maturation
Engineering & Conjugation
Custom design: Fc-fusion, chelation, fluorophores, nanobody-drug-conjugates, linkers, toxins, multispecifics
Preclinical Readiness
Expression, purification, in vitro profiling, Radiopharmaceutical and CAR-T optimization, GMP transfer support
Why Choose Cortalix
Hybrid Flexibility – Choose immune libraries, synthetic libraries, or both
Animal-Free Options – Synthetic library track is fully animal-free
Deep Binding Potential – Immune libraries offer strong, specific VHHs
Full Engineering Support – From discovery to preclinical applications
Experienced Team – Decades of combined VHH and antibody development expertise
Contact Us
Let’s find your best VHH Nanobody strategy. Contact us today for a free intake session. We’ll help map the best route from target to lead candidate.
Latest News and Events
CORTALIX will be present at Antibody Industrial Symposium (AIS) in Tours, France, June 25-26 2025
Cortalix receives investment from Future Tech Ventures and Rabobank Innovation
Cortalix will present at PepTalk San Diego, CA, January 13-16 2025
Cortalix will present at Festival of Biologics in Basel, Switzerland, 15-17 October 2024
Cortalix is Supported By
Contact Us
If you would like to know more about our organization, or would like to know how we can support your projects, please complete the contact form. We will contact you shortly.