VHH Antibody discovery
SMART
VHH ANTIBODY
DISCOVERY
1014 functional possibilities. Zero compromise
Ribosomal display diversity combined with phage display precision
in one integrated VHH discovery platform
Smart VHH Antibody Discovery
Cortalix offers cutting-edge VHH antibody discovery & development services through a unique, dual-platform approach, combining the massive functional diversity of ribosomal display with the battle-tested robustness of phage display:
- SYNTHETIC LIBRARIES: animal-free, rapid, and built for scale. Powered by ribosomal display with a functional diversity of up to 1014, enabling deep coverage of sequence space, ideal for fast screening, modular multispecific formats, or high-throughput projects.
- IMMUNE LIBRARIES: derived from llama immunizations and screened via phage display. Providing high natural affinity and deep epitope coverage for complex or challenging targets.
Our hybrid platform, ribosomal display for breadth, phage display for precision, gives you the flexibility to choose the best discovery route for each project, with seamless downstream integration.
Whether you’re developing a diagnostic, therapeutic, or analytical research tool, we support you all the way, with expert services in CDR grafting, humanization, affinity maturation, conjugation, and more.
What We Offer
Discovery via Immune & Synthetic Libraries
Lead Optimization
CDR grafting, humanization, stability profiling, affinity maturation
Engineering & Conjugation
Custom design: Fc-fusion, chelation, fluorophores, nanobody-drug-conjugates, linkers, toxins, multispecifics
Preclinical Readiness
Expression, purification, in vitro profiling, Radiopharmaceutical and CAR-T optimization, GMP transfer support
Why Choose Cortalix
Animal-Free Options: Synthetic library track is fully animal-free
Deep Binding Potential: Immune libraries offer strong, specific VHHs
Full Engineering Support: From discovery to preclinical applications
Experienced Team: Decades of combined VHH antibody development expertise
Contact Us
Let’s find your best VHH Antibody strategy. Contact us today for a free intake session. We’ll help map the best route from target to lead candidate.
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