VHH Nanobody
Discovery & Development

up to 1014 functional VHH variants Synthetic, humanized FC8™ framework

Website temporarily unavailable

Following a recent PHP vulnerability, we have taken our website offline as a precaution. We have no indication that we are affected, and the site will return as soon as the proper safeguards are in place.

Smart VHH Nanobody Discovery

Cortalix offers VHH nanobody discovery and development services built on FC8™, our proprietary synthetic scaffold framework engineered from the ground up for clinical translation, powered by a sequential ribosomal display and phage display pipeline.

VHH Discovery via FC8™ Synthetic Libraries

Ribosomal display transitioning seamlessly into phage display. Animal-free, fast, and built for therapeutic development.

Immune VHH Discovery

Target-specific discovery from llama or alpaca immune libraries with naturally affinity-matured binders.

Lead Optimization

CDR grafting, humanization, stability profiling and affinity maturation.

Engineering & Conjugation

Fc-fusions, chelation, fluorophores, nanobody-drug-conjugates, linkers, toxins and multispecifics.

Preclinical Readiness

Expression, purification, in vitro profiling, radiopharmaceutical and CAR-T optimization, GMP transfer support.

Contact Us

Ready to eliminate your lead optimization bottleneck? Get in touch for a free scientific intake session, and we’ll map the fastest route to a clinical-ready VHH candidate. Our online contact form is unavailable during maintenance.

CORTALIX BV
MediTech Center
L.J.Zielstraweg 1
9713 GX Groningen
The Netherlands

Cortalix is supported by

European Union SNN Noord-Nederland Eureka Eurostars Rabobank Future Tech Ventures University Medical Center Groningen University of Groningen